There were many photographers named Griffin between 1880 and 1920. They ranged from Maryland to Nebraska, Pennsylvania to Alabama. The most likely photographer for this cabinet card was
(12 Jul 1852 - 1920)
In 1868 the Omaha, NE, city directory lists one Charles Griffin as a photographer at 230 Farnam; William Griffin is not shown; he would be only 16
In 1870, at 18, William Griffin was working with Charles Griffin photograph studio (over 237 Douglas) in Omaha, NE. Both are also living at the same address. Charles Griffin has not been found to be a brother or an uncle to William. There were some large families in that era. The relationship, if any, is not known at this time.
In 1880 the US census shows William as a farmer. Then the 1900 US census shows him as married, living in Hebron, NE, as a photographer.
The 1910 US census shows he is still a photographer in Hebron, NE, but the 1920 census says he has no occupation and his wife Lydia is a laundress. He dies later in 1920 at age 67.
There are a lot of gaps in the documentation of William Griffin but he is consistently the photographer from Hebron, NE. This cabinet card was probably finished between 1880 and 1920 when he was working without a partner. The design of the card suggests 1890 or after.
Cor 3rd and Lincoln
example from auction site
Note that his card is the same design as the top card on this page. All others are different, no two alike.